Cancerkin News…
Hyde Park Walk update......
This year over £40,000 has been raised in donations and sponsorship for the Hyde Park Walk. The pictures for this year’s walk can be viewed on our Flickr and Facebook pages. If you have any pictures which you would like to share with us you can do so by uploading them onto our Facebook wall. Finally, please remember to send in your sponsorship money before 13th August and ensure that all cheques are made payable to Cancerkin.
La Bohème......
Cancerkin’s opera evening is next weekend and we still have tickets available! For more information or to order tickets please contact Lauren Newton on 020 7830 2323 or at l.newton@cancerkin.org.uk. All proceeds will go towards the creation of a Young Women’s Support Group at Cancerkin.
In the News…
Woman’s breast cancer diagnosis was wrong…
In 2007, a pathologist in Michigan found what was believed to be the earliest stage of breast cancer from a biopsy. The patient, Ms Long endured an extensive surgery, leaving her right breast missing a chunk the size of a golf ball.
In 2008 however, she was told that the pathologist had made a mistake as her new doctor was sure she never had the disease, called ductal carcinoma in situ (D.C.I.S), meaning the surgery, radiation, drugs and the fear had all been unnecessary. Miss Long, who is a registered nurse, told the New York Times that ‘”I never should have had to go through what I did”.
Like many women, Ms Long believed that a breast biopsy was the most reliable way to identify cancer. However, it turns out that diagnosing the earliest stage of breast cancer can be difficult.
Advances over the past 3 decades in mammography and other imaging techniques have meant that pathologists must form opinions on even the smallest breast lesions; some may even be the size of a grain of salt. According to some doctors deciphering the difference between lesions which are benign and early stage breast cancer is challenging.
According to Dr. Shahla Masood, who is the head of pathology at the University of Florida, College of Medicine, “There are studies that show that diagnosing these borderline breast lesions occasionally comes down to the flip of a coin.”
Dr Vi, who diagnosed Ms Long with DCIS was not board certified and has stated that he reads around 50 breast biopsies a year, far less than the leading pathologists say is needed in dealing with difficult breast cancer cases.
In response to a lawsuit brought by Ms. Long, Dr. Vi maintains that she had cancer and that two board-certified pathologists had agreed with his diagnosis.
However leading experts who reviewed Ms. Long’s case disagreed stating that her local pathologists “blew the diagnosis.”
Read more here.
African ancestry......
Researchers at the University of Michigan have found that African ancestry increases the chances of triple negative breast cancer, an overly aggressive form. A study of breast cancer in different ethnic groups showed that 82% of African women who had breast cancer had the triple negative variety as opposed to 26% in African Americans and only 16% in white Americans.
Triple negative cancer is negative for certain markers used in identifying suitable treatments. Most medical advances have come about using these markers and therefore the treatment options for triple negative breast cancer are limited. The researchers used 581 African Americans and 1008 white Americans in Detroit as well as 75 Ghanaians from the Komfo Anokye Teaching Hospital in Ghana. More on the story here.
Cancerkin Team
Friday 23rd July 2010
Wednesday, 28 July 2010
Friday, 16 July 2010
On the pulse...for people affected by breast cancer
On the pulse
Cancerkin News…
Many hands make light work…
Cancerkin are pleased to welcome another new intern, Guy Mollett. Guy will be with Cancerkin for a month before he returns to school for his A Levels, after which he hopes to go to University to study medicine. Guy has been helping with all things financial, processing our Hyde Park Walk and La Boheme sponsorship. If you have yet to send yours in please do at your earliest convenience so that we can get it all accounted for whilst we have Guy’s valuable help.
In the News…
Another young woman to the count…
Nicola Duffy was diagnosed with stage one breast cancer at the tender age of 31. With a history of breast cancer throughout her grandmothers, mother and aunts the risk was always there, but for Nicola, and many more women like her, the diagnosis came much earlier than expected. This is the third story of a young woman with breast cancer that has featured in the press in so many months; highlighting the increase in of cancer in those under 50. Her story, published in last week’s Stylist magazine, documents the trouble she had fitting in doctor’s appointments around her ‘demanding role in recruitment’ and her struggle with stopping it ‘getting in the way of my dreams’. Nicola also quite happily disclosed the fear she felt when she decided to have a double mastectomy and the worry about how this would affect her relationship with her boyfriend who had ‘assured me he would still love me, no matter what’.
Despite its relatively short length, I wonder if Stylist or indeed Nicola herself realised how many crucial issues for young women the article touched upon. The Cancerkin Young Women’s Support Group, currently in the planning stage, will respond to the issues that Nicola and many others like her experience. Worries about work pressures, career prospects, fertility, sexuality, body image, relationships, genetics etc. Our opera evening, which has been praised by Simon Thomas(opera reviewer for What’s On Stage) on Twitter is raising money to help establish this support group. If you, or anyone you know would like more information about the Young Women’s Group or the Opera Gala please contact Lauren Newton on l.newton@cancerkin.org.uk . To read Simon Thomas’ Review click here.
Breakthrough in treating aggressive breast cancer could be on the way….
HER2 – a form of breast cancer which encourages the disease to spread around the body, often causing fatal secondary tumours, affects around 9,000 women each year- approximately 1 in 5 of UK women suffering with the disease. A team in Edinburgh have now discovered the gene that causes HER2 to spread so fast and dangerously. This discovery means that new drugs will be able to be manufactured to block the gene’s function and therefore prevent the cancer from spreading to other parts of the body. Research leader Dr Elad Katz, from the Breakthrough Breast Cancer Research Unit, said: “With all cancers, the key is working out how they form and spread. Identifying this gene’s key role in the spread of this type of breast cancer is a significant finding.” Professor David Harrison, Director of the Unit agrees saying:“It is exciting to know there is a drug out there which could potentially stop this process happening and save the lives of women with breast cancer.” Read the full details here.
A creative path to empathy…
Comic books are increasingly being used by medical lecturers to teach their students medicine from the patients view. The comic strips show how treatments and diagnosis affect the patients and their families and are being used in universities to help students understand the doctor-patient relationship and empathy. ‘Cancer Vixen’ a comic about a women’s experience of breast cancer is one of these graphic novels; the comic can be found in the Cancerkin reference library for any of you who would like to take a peek. Read the full story here.
Cancer survival rates have nearly doubled in the last 30 years…
Although the hippie age is over with the principles of freedom, truth, love and peace almost dead in the water, BBC news online published some figures this week which should make us happy to be living in the fast-paced 21st century. A recent comparative study found that compared to 1970 the chance of surviving for 10 years following a cancer diagnosis has doubled (for most common cancers only). For breast cancer alone survival rates have increased from 40% to 77%; a massive leap in progress. The increases have been attributed to advances in medical techniques and treatments, thorough and accessible screening processes and an increased knowledge of cancer and its symptoms helping to result in earlier detection. To read the full article and see the statistics of other cancer forms please click here.
Lauren Newton 15th July 2010
l.newton@cancerkin.org.uk
Cancerkin News…
Many hands make light work…
Cancerkin are pleased to welcome another new intern, Guy Mollett. Guy will be with Cancerkin for a month before he returns to school for his A Levels, after which he hopes to go to University to study medicine. Guy has been helping with all things financial, processing our Hyde Park Walk and La Boheme sponsorship. If you have yet to send yours in please do at your earliest convenience so that we can get it all accounted for whilst we have Guy’s valuable help.
In the News…
Another young woman to the count…
Nicola Duffy was diagnosed with stage one breast cancer at the tender age of 31. With a history of breast cancer throughout her grandmothers, mother and aunts the risk was always there, but for Nicola, and many more women like her, the diagnosis came much earlier than expected. This is the third story of a young woman with breast cancer that has featured in the press in so many months; highlighting the increase in of cancer in those under 50. Her story, published in last week’s Stylist magazine, documents the trouble she had fitting in doctor’s appointments around her ‘demanding role in recruitment’ and her struggle with stopping it ‘getting in the way of my dreams’. Nicola also quite happily disclosed the fear she felt when she decided to have a double mastectomy and the worry about how this would affect her relationship with her boyfriend who had ‘assured me he would still love me, no matter what’.
Despite its relatively short length, I wonder if Stylist or indeed Nicola herself realised how many crucial issues for young women the article touched upon. The Cancerkin Young Women’s Support Group, currently in the planning stage, will respond to the issues that Nicola and many others like her experience. Worries about work pressures, career prospects, fertility, sexuality, body image, relationships, genetics etc. Our opera evening, which has been praised by Simon Thomas(opera reviewer for What’s On Stage) on Twitter is raising money to help establish this support group. If you, or anyone you know would like more information about the Young Women’s Group or the Opera Gala please contact Lauren Newton on l.newton@cancerkin.org.uk . To read Simon Thomas’ Review click here.
Breakthrough in treating aggressive breast cancer could be on the way….
HER2 – a form of breast cancer which encourages the disease to spread around the body, often causing fatal secondary tumours, affects around 9,000 women each year- approximately 1 in 5 of UK women suffering with the disease. A team in Edinburgh have now discovered the gene that causes HER2 to spread so fast and dangerously. This discovery means that new drugs will be able to be manufactured to block the gene’s function and therefore prevent the cancer from spreading to other parts of the body. Research leader Dr Elad Katz, from the Breakthrough Breast Cancer Research Unit, said: “With all cancers, the key is working out how they form and spread. Identifying this gene’s key role in the spread of this type of breast cancer is a significant finding.” Professor David Harrison, Director of the Unit agrees saying:“It is exciting to know there is a drug out there which could potentially stop this process happening and save the lives of women with breast cancer.” Read the full details here.
A creative path to empathy…
Comic books are increasingly being used by medical lecturers to teach their students medicine from the patients view. The comic strips show how treatments and diagnosis affect the patients and their families and are being used in universities to help students understand the doctor-patient relationship and empathy. ‘Cancer Vixen’ a comic about a women’s experience of breast cancer is one of these graphic novels; the comic can be found in the Cancerkin reference library for any of you who would like to take a peek. Read the full story here.
Cancer survival rates have nearly doubled in the last 30 years…
Although the hippie age is over with the principles of freedom, truth, love and peace almost dead in the water, BBC news online published some figures this week which should make us happy to be living in the fast-paced 21st century. A recent comparative study found that compared to 1970 the chance of surviving for 10 years following a cancer diagnosis has doubled (for most common cancers only). For breast cancer alone survival rates have increased from 40% to 77%; a massive leap in progress. The increases have been attributed to advances in medical techniques and treatments, thorough and accessible screening processes and an increased knowledge of cancer and its symptoms helping to result in earlier detection. To read the full article and see the statistics of other cancer forms please click here.
Lauren Newton 15th July 2010
l.newton@cancerkin.org.uk
Friday, 9 July 2010
On the pulse...
On the pulse
Cancerkin News…
Hyde Park Walk sponsorship…
Thank you to all of you who have been sending in your sponsorship for the Hyde Park Walk - the fundraising total is steadily on the rise! For those of you who have yet to send in your monies, remember to do so before Friday 13th August, when our top 3 fundraisers will be awarded with luxury products kindly donated by Floris. Please remember to make all cheques payable to Cancerkin and where possible please avoid sending cash in the post. Please contact l.newton@cancerkin.org.uk if you have any queries about sponsorship.
Renowned opera reviewer gives Cancerkin opera event thumbs up…
Simon Thomas, top opera reviewer for magazine and online arts listing, What’s On Stage, has written a fantastic review of Cancerkin’s up and coming opera gala evening at the Soho Theatre, London- rating it as a must see production. If you would like to join us for the event, which begins a 6.30pm on Saturday 31st July for a champagne and canapés reception with the cast then please contact l.newton@cancerkin.org.uk for further information and ticket requests. To view Simon Thomas’ report please click here or look up his blogs for Cancerkin on Twitter here.
In the News…
Beat cancer by having fun…
A study at Ohio University has taken mice that have cancer out of their usual commune of 5 and have placed them in a more sociable group of around 15-20 other mice, to see if this has an effect on their response to their cancer. Alongside the extra housemates the mice were given more toys, hiding space and running wheels. The result of this new environment saw the mice’s tumours become 43% smaller with a 77% reduction in mass and around 5% of the mice showing no evidence of the cancer disease after 3 weeks in the new home. These effects were not replicated in the mice that were kept in the standard accommodation.
Study lead Prof. Matthew During said “We’re really showing that you can’t look at a disease like cancer in isolation. For too long physicians and others have stuck to what they know- surgery, chemo radiotherapy. If we look at people more in terms of their perceptions of disease and environment, we could realise a profound influence on cancer”. This research helps to validate the views that a positive mental attitude and a safe and secure environment can help to play an important role in beating breast cancer; an outlook Cancerkin work to promote every day. This story featured on page 14 of Friday morning’s Metro.
Cancer genealogy poses threat to men….
Men who are carriers of a faulty BRCA2 gene have a 1 in 15 chance of being diagnosed with breast cancer by the time they are 70 The Daily Mail reported this week. This figure is opposed to the 1 in 1000 chance men in the general population have of developing breast cancer. The gene can be passed down through generations regardless of the sex of the newborn baby; a fact that will change many people’s views on the link between genetics and breast cancer. Each year in the UK 300 men are diagnosed with breast cancer, compared to the 45,000 for women. Read the full article here
Positive results for new breast cancer drug….
A new drug sponsored by AstraZeneca has caused positive results in its latest trial. Olaparib, as the drug is called, effects cancers caused by faulty BRCA 1 and 2 genes. In Stage II trials for breast cancer and ovarian cancer, 111 patients were given the drug in small or large amounts. In the breast cancer trial of the patients who received the larger dose, 40% had a significant reduction in tumour size and tumours were stopped from increasing for about 6 months. To read full details of the trial please click here
Could being overweight really lower the risk of developing breast cancer..?
A study has found that being overweight when young may reduce the chances of developing breast cancer in later life. Scientists at Brigham and Women’s Hospital in Boston undertook a 17 year study to research the effects of weight on the development of breast cancer. The study which took into account the records of 188,860 women found that an increased level of body fat, particularly during adolescence decreases the risk of breast cancer in pre and post-menopausal women. However the dangers of being overweight are well known and pose many other risks in themselves. Please click here to read the full article.
Lauren Newton 9th July 2010
l.newton@cancerkin.org.uk
Cancerkin News…
Hyde Park Walk sponsorship…
Thank you to all of you who have been sending in your sponsorship for the Hyde Park Walk - the fundraising total is steadily on the rise! For those of you who have yet to send in your monies, remember to do so before Friday 13th August, when our top 3 fundraisers will be awarded with luxury products kindly donated by Floris. Please remember to make all cheques payable to Cancerkin and where possible please avoid sending cash in the post. Please contact l.newton@cancerkin.org.uk if you have any queries about sponsorship.
Renowned opera reviewer gives Cancerkin opera event thumbs up…
Simon Thomas, top opera reviewer for magazine and online arts listing, What’s On Stage, has written a fantastic review of Cancerkin’s up and coming opera gala evening at the Soho Theatre, London- rating it as a must see production. If you would like to join us for the event, which begins a 6.30pm on Saturday 31st July for a champagne and canapés reception with the cast then please contact l.newton@cancerkin.org.uk for further information and ticket requests. To view Simon Thomas’ report please click here or look up his blogs for Cancerkin on Twitter here.
In the News…
Beat cancer by having fun…
A study at Ohio University has taken mice that have cancer out of their usual commune of 5 and have placed them in a more sociable group of around 15-20 other mice, to see if this has an effect on their response to their cancer. Alongside the extra housemates the mice were given more toys, hiding space and running wheels. The result of this new environment saw the mice’s tumours become 43% smaller with a 77% reduction in mass and around 5% of the mice showing no evidence of the cancer disease after 3 weeks in the new home. These effects were not replicated in the mice that were kept in the standard accommodation.
Study lead Prof. Matthew During said “We’re really showing that you can’t look at a disease like cancer in isolation. For too long physicians and others have stuck to what they know- surgery, chemo radiotherapy. If we look at people more in terms of their perceptions of disease and environment, we could realise a profound influence on cancer”. This research helps to validate the views that a positive mental attitude and a safe and secure environment can help to play an important role in beating breast cancer; an outlook Cancerkin work to promote every day. This story featured on page 14 of Friday morning’s Metro.
Cancer genealogy poses threat to men….
Men who are carriers of a faulty BRCA2 gene have a 1 in 15 chance of being diagnosed with breast cancer by the time they are 70 The Daily Mail reported this week. This figure is opposed to the 1 in 1000 chance men in the general population have of developing breast cancer. The gene can be passed down through generations regardless of the sex of the newborn baby; a fact that will change many people’s views on the link between genetics and breast cancer. Each year in the UK 300 men are diagnosed with breast cancer, compared to the 45,000 for women. Read the full article here
Positive results for new breast cancer drug….
A new drug sponsored by AstraZeneca has caused positive results in its latest trial. Olaparib, as the drug is called, effects cancers caused by faulty BRCA 1 and 2 genes. In Stage II trials for breast cancer and ovarian cancer, 111 patients were given the drug in small or large amounts. In the breast cancer trial of the patients who received the larger dose, 40% had a significant reduction in tumour size and tumours were stopped from increasing for about 6 months. To read full details of the trial please click here
Could being overweight really lower the risk of developing breast cancer..?
A study has found that being overweight when young may reduce the chances of developing breast cancer in later life. Scientists at Brigham and Women’s Hospital in Boston undertook a 17 year study to research the effects of weight on the development of breast cancer. The study which took into account the records of 188,860 women found that an increased level of body fat, particularly during adolescence decreases the risk of breast cancer in pre and post-menopausal women. However the dangers of being overweight are well known and pose many other risks in themselves. Please click here to read the full article.
Lauren Newton 9th July 2010
l.newton@cancerkin.org.uk
Monday, 28 June 2010
On the pulse...for people affected by breast cancer
On the pulse
Cancerkin’s News…
Music Therapy…
Cancerkin is pleased to announce the pilot introduction of a brand new therapy: Music Therapy. Therapist, Karina Gretere, will be running three taster sessions on September 24th, October 1st and October 8th. Karina will use improvisation to draw her patients into shared music making, engaging in a person’s innate creativity and working with difficulties affecting their well being. If you are interested in taking part in these sessions or would like more general information about music therapy please speak to Jean on reception.
New Intern…
Another week, another intern! This summer, Cancerkin is lucky enough to have the help of Athena Tasou. Athena, who is currently studying a Psychology degree at Oxford Brookes, will be in the Cancerkin office three days a week to assist on fundraising, PR and events. We are extremely happy to have her and wish her the best of luck during her time here.
In the News…
A gift of life….
In a story as good as any Hollywood blockbuster, 37 year old Nikki Blunden, mum to a four year old little boy, has been given the gift of life by a complete stranger. Nikki, whose breast cancer had spread to her liver, lymph nodes and brain, was denied life-prolonging drugs by her health authority who claimed they were too expensive, and thus was not expecting to live out the year. However, in a lucky twist of fate businessman Nazir Mohammed heard of Nikki’s story through a friend and has generously donated the £25,000 needed for the treatment, saying ‘If I can give her the chance of a few more months by paying for the drug, I’m happy to do that.’
Although this story reminds us all that generosity and selflessness is still alive in our society, it is yet another example of the emergent number of young women suffering with cancer. Cancerkin’s La Boheme benefit opera evening will be raising money to help these women by setting up a Young Women’s Support Group later this year. If you would like to attend the opera or would like more information on the Young Women’s Support Group please contact l.newton@cancerkin.org.uk .
This story was featured in the Metro (p34) on Thursday 24th June
Double- mastectomy for mother and son….
Following the death of her mother from ovarian cancer when she was just 12 years old, and the later diagnosis of her two sisters, (both with breast cancer), Lynda Skillom agonised for months over whether to have a double- mastectomy. After choosing to go through with the surgery, Lynda was dealt another blow, as her only child, 29 year old son Cedric was also found to have pre-cancerous tissues in both breasts.
After informing the doctor of her family history with cancer and herself having cancerous lumps removed from both breasts, Linda was tested for a mutation in the BRCA2 gene; a mutation which drastically increases a carrier’s risk of breast and other forms of cancer. Sure enough the result was positive.
Breast cancers are five times more likely in women who inherit the BRAC2 mutation. Furthermore, cancer in carriers of the faulty gene is also notoriously aggressive. Knowing this information Lynda took decisive steps to prevent her cancer returning, opting to have both a double mastectomy and her ovaries removed- a step she took to prevent ovarian cancer, a disease linked to the BRCA2 mutation.
After experiencing tenderness and chest pain for around 2 years, Lynda’s son Cedric also fell victim to the BRCA2 gene, and he was promptly diagnosed with breast cancer. Following in the footsteps of his mother, Cedric too opted for a double- mastectomy. Commenting on his drastic decision Cedric says, "Most of all I felt surprised, really surprised. I didn't know that men could get breast cancer. As a man it felt strange, but I wanted to take care of it there and then, so I wouldn't have to worry about it coming back.”
"While breast cancer is rare in men, those who carry the BRCA2 gene are at greater risk of getting the disease," says Dr Patricia Robinson, the oncologist who treated mother and son at the Loyola University Health System, in Chicago. "A double mastectomy is often the best option for long-term prognosis for these patients.” A fault in the BRCA2 gene, which is needed for effective DNA repair, is thought to be responsible for about 10 per cent of breast-cancer cases in men. For male carriers of BRCA2 mutation, the lifetime risk of the disease is as high as 10 per cent. It also seems to raise the risk of prostate cancer, causing a particularly aggressive form of the disease.
Read the Skillom’s full story here
Lauren Newton 18th June 2010
l.newton@cancerkin.org.uk
Cancerkin’s News…
Music Therapy…
Cancerkin is pleased to announce the pilot introduction of a brand new therapy: Music Therapy. Therapist, Karina Gretere, will be running three taster sessions on September 24th, October 1st and October 8th. Karina will use improvisation to draw her patients into shared music making, engaging in a person’s innate creativity and working with difficulties affecting their well being. If you are interested in taking part in these sessions or would like more general information about music therapy please speak to Jean on reception.
New Intern…
Another week, another intern! This summer, Cancerkin is lucky enough to have the help of Athena Tasou. Athena, who is currently studying a Psychology degree at Oxford Brookes, will be in the Cancerkin office three days a week to assist on fundraising, PR and events. We are extremely happy to have her and wish her the best of luck during her time here.
In the News…
A gift of life….
In a story as good as any Hollywood blockbuster, 37 year old Nikki Blunden, mum to a four year old little boy, has been given the gift of life by a complete stranger. Nikki, whose breast cancer had spread to her liver, lymph nodes and brain, was denied life-prolonging drugs by her health authority who claimed they were too expensive, and thus was not expecting to live out the year. However, in a lucky twist of fate businessman Nazir Mohammed heard of Nikki’s story through a friend and has generously donated the £25,000 needed for the treatment, saying ‘If I can give her the chance of a few more months by paying for the drug, I’m happy to do that.’
Although this story reminds us all that generosity and selflessness is still alive in our society, it is yet another example of the emergent number of young women suffering with cancer. Cancerkin’s La Boheme benefit opera evening will be raising money to help these women by setting up a Young Women’s Support Group later this year. If you would like to attend the opera or would like more information on the Young Women’s Support Group please contact l.newton@cancerkin.org.uk .
This story was featured in the Metro (p34) on Thursday 24th June
Double- mastectomy for mother and son….
Following the death of her mother from ovarian cancer when she was just 12 years old, and the later diagnosis of her two sisters, (both with breast cancer), Lynda Skillom agonised for months over whether to have a double- mastectomy. After choosing to go through with the surgery, Lynda was dealt another blow, as her only child, 29 year old son Cedric was also found to have pre-cancerous tissues in both breasts.
After informing the doctor of her family history with cancer and herself having cancerous lumps removed from both breasts, Linda was tested for a mutation in the BRCA2 gene; a mutation which drastically increases a carrier’s risk of breast and other forms of cancer. Sure enough the result was positive.
Breast cancers are five times more likely in women who inherit the BRAC2 mutation. Furthermore, cancer in carriers of the faulty gene is also notoriously aggressive. Knowing this information Lynda took decisive steps to prevent her cancer returning, opting to have both a double mastectomy and her ovaries removed- a step she took to prevent ovarian cancer, a disease linked to the BRCA2 mutation.
After experiencing tenderness and chest pain for around 2 years, Lynda’s son Cedric also fell victim to the BRCA2 gene, and he was promptly diagnosed with breast cancer. Following in the footsteps of his mother, Cedric too opted for a double- mastectomy. Commenting on his drastic decision Cedric says, "Most of all I felt surprised, really surprised. I didn't know that men could get breast cancer. As a man it felt strange, but I wanted to take care of it there and then, so I wouldn't have to worry about it coming back.”
"While breast cancer is rare in men, those who carry the BRCA2 gene are at greater risk of getting the disease," says Dr Patricia Robinson, the oncologist who treated mother and son at the Loyola University Health System, in Chicago. "A double mastectomy is often the best option for long-term prognosis for these patients.” A fault in the BRCA2 gene, which is needed for effective DNA repair, is thought to be responsible for about 10 per cent of breast-cancer cases in men. For male carriers of BRCA2 mutation, the lifetime risk of the disease is as high as 10 per cent. It also seems to raise the risk of prostate cancer, causing a particularly aggressive form of the disease.
Read the Skillom’s full story here
Lauren Newton 18th June 2010
l.newton@cancerkin.org.uk
Friday, 18 June 2010
On the pulse...for people affected by breast cancer
On the pulse
Cancerkin’s News…
Hyde Park Walk…
On behalf of everyone at Cancerkin I would like to say a very BIG thank you to everyone who attended our Hyde Park Walk on Sunday. It was a fantastic event; with beautiful weather, a buzzing atmosphere and the biggest turnout Cancerkin has ever seen. I sincerely hope you all enjoyed it as much as we here at the office did. All that is left for you to do is send in your sponsorships forms and money (in cheque form where possible) to: The Cancerkin Centre, The Royal Free Hospital, Pond Street, Hampstead, NW3 3QG. There are three prizes (donated by Floris) up for grabs for the top fundraisers. To be in with a chance of getting your hands on these you MUST send your sponsorship money in before Friday 13th August. For those of you who have fundraised via Just Giving do not fear, your total will also be included in the prize draw.
There were a few items that were left behind on the day. If you think any of the following could be yours please drop me an email at l.newton@cancerkin.org.uk.
1. A pair of tortoise shell sunglasses, left on the O-Z registration desk
2. A DOMKE protective wrap, most likely an attachment to a rucksack- left in the bandstand
3. A ring found along the Serpentine route.
In the News…
Lisa Lynch: A young woman with breast cancer….
This week Lisa Lynch, shared the story of her invasive breast cancer diagnosis at the age of only 28 with the Guardian, ahead of the launch of her new book, ‘The C-Word’. In keeping with the digital media generation, the book was born out of the tales Lisa uploaded onto her blogspace ‘Alright Tit, where she wittingly documented, "the frustrating, life-altering, sheer bloody pain-in-the-arse inconvenience of getting breast cancer at 28." This however was no normal blog space, it managed to gain 140,000 hits within a year and soon captivated QI presenter Stephen Fry, who called her “funny and brilliant”.
Other than the sardonic, (and yet positive!) retelling of Lisa’s own experiences, The C-Word explores the difficult change in familial dynamics that face young women with breast cancer. By documenting the feelings that her parents experienced in her cancer journey, Lisa touches on a key question for many parents whose children are sick: is it any less painful for the parents of an adult child to have to cope with the news of such a devastating prognosis? Indeed Lisa’s mother said "I felt guilty that it wasn't me. It seemed so unfair. Just because your child has grown up and left home, it doesn't mean they are not your child”. Her father Ian adds: "As a parent you feel totally helpless."
Lisa’s story is a vibrantly honest one, and touches on some of the issues that we at Cancerkin want to help our young women to deal with. With the beginnings of a Young Women’s Group in place, it is our vision that we will help women like Lisa in dealing with issues such as: telling the parents, telling the children, career and job prospects, fertility, genetics, sexuality and body image. Our fundraising opera evening on Saturday 31st July will be raising money for our Young Women’s Group. If you feel that you would benefit from the group, would like to offer a donation towards the establishment of the group or would like tickets to our opera please email me at l.newton@cancerkin.org.uk.
Read the rest of Lisa’s inspiring story here
A common blood pressure drug found to increase risk of cancer
A new research study has found that Angiotensin-receptor blockers (ARBs), commonly used to treat high blood pressure, heart failure and kidney damage pose a risk of cancer to anyone taking the tablets.
The research which was carried out at Case Western Reserve University in Ohio and published on line by The Lancet Oncology journal, included 13 trials of the drugs on more than 150,000 patients. The results found, according to researchers: “The increased risk of new cancer occurrence is modest but significant …[However] the finding of a 1.2 per cent increase in absolute cancer risk over an average of 4 years needs to be interpreted in view of the estimated 41 per cent background lifetime cancer risk.”
Senior Cardiac nurse for the British Heart Foundation , Judy O’Sullivan, said: “This analysis of previous research is inconclusive and anyone taking ARBs to treat their heart disease, or risk of developing it, shouldn’t stop based on this alone. Mark Lerwick of Cancer Research UK, too called for a more in-depth study but noted that: "It’s important that we try to understand all the side effects of drugs so that people can make an informed choice about their treatment. “ Read the full article here
LaurenNewton 18thJune 2010
l.newton@cancerkin.org.uk
Cancerkin’s News…
Hyde Park Walk…
On behalf of everyone at Cancerkin I would like to say a very BIG thank you to everyone who attended our Hyde Park Walk on Sunday. It was a fantastic event; with beautiful weather, a buzzing atmosphere and the biggest turnout Cancerkin has ever seen. I sincerely hope you all enjoyed it as much as we here at the office did. All that is left for you to do is send in your sponsorships forms and money (in cheque form where possible) to: The Cancerkin Centre, The Royal Free Hospital, Pond Street, Hampstead, NW3 3QG. There are three prizes (donated by Floris) up for grabs for the top fundraisers. To be in with a chance of getting your hands on these you MUST send your sponsorship money in before Friday 13th August. For those of you who have fundraised via Just Giving do not fear, your total will also be included in the prize draw.
There were a few items that were left behind on the day. If you think any of the following could be yours please drop me an email at l.newton@cancerkin.org.uk.
1. A pair of tortoise shell sunglasses, left on the O-Z registration desk
2. A DOMKE protective wrap, most likely an attachment to a rucksack- left in the bandstand
3. A ring found along the Serpentine route.
In the News…
Lisa Lynch: A young woman with breast cancer….
This week Lisa Lynch, shared the story of her invasive breast cancer diagnosis at the age of only 28 with the Guardian, ahead of the launch of her new book, ‘The C-Word’. In keeping with the digital media generation, the book was born out of the tales Lisa uploaded onto her blogspace ‘Alright Tit, where she wittingly documented, "the frustrating, life-altering, sheer bloody pain-in-the-arse inconvenience of getting breast cancer at 28." This however was no normal blog space, it managed to gain 140,000 hits within a year and soon captivated QI presenter Stephen Fry, who called her “funny and brilliant”.
Other than the sardonic, (and yet positive!) retelling of Lisa’s own experiences, The C-Word explores the difficult change in familial dynamics that face young women with breast cancer. By documenting the feelings that her parents experienced in her cancer journey, Lisa touches on a key question for many parents whose children are sick: is it any less painful for the parents of an adult child to have to cope with the news of such a devastating prognosis? Indeed Lisa’s mother said "I felt guilty that it wasn't me. It seemed so unfair. Just because your child has grown up and left home, it doesn't mean they are not your child”. Her father Ian adds: "As a parent you feel totally helpless."
Lisa’s story is a vibrantly honest one, and touches on some of the issues that we at Cancerkin want to help our young women to deal with. With the beginnings of a Young Women’s Group in place, it is our vision that we will help women like Lisa in dealing with issues such as: telling the parents, telling the children, career and job prospects, fertility, genetics, sexuality and body image. Our fundraising opera evening on Saturday 31st July will be raising money for our Young Women’s Group. If you feel that you would benefit from the group, would like to offer a donation towards the establishment of the group or would like tickets to our opera please email me at l.newton@cancerkin.org.uk.
Read the rest of Lisa’s inspiring story here
A common blood pressure drug found to increase risk of cancer
A new research study has found that Angiotensin-receptor blockers (ARBs), commonly used to treat high blood pressure, heart failure and kidney damage pose a risk of cancer to anyone taking the tablets.
The research which was carried out at Case Western Reserve University in Ohio and published on line by The Lancet Oncology journal, included 13 trials of the drugs on more than 150,000 patients. The results found, according to researchers: “The increased risk of new cancer occurrence is modest but significant …[However] the finding of a 1.2 per cent increase in absolute cancer risk over an average of 4 years needs to be interpreted in view of the estimated 41 per cent background lifetime cancer risk.”
Senior Cardiac nurse for the British Heart Foundation , Judy O’Sullivan, said: “This analysis of previous research is inconclusive and anyone taking ARBs to treat their heart disease, or risk of developing it, shouldn’t stop based on this alone. Mark Lerwick of Cancer Research UK, too called for a more in-depth study but noted that: "It’s important that we try to understand all the side effects of drugs so that people can make an informed choice about their treatment. “ Read the full article here
LaurenNewton 18thJune 2010
l.newton@cancerkin.org.uk
Friday, 11 June 2010
On the pulse...for people affected by breast cancer
On the pulse
Cancerkin’s News…
Hyde Park Walk…
Our Hyde Park Walk takes place this Sunday, 13th June. Registration will be between 9-10.30am with the walk finishing at approximately 2.30pm. Graeme Le Saux, ex Chelsea and England football player will be there to open the event. Entry will be available on the day so please feel free to bring anyone along with you who would like to take part. As always many hands make light work, so if you know someone who would like to volunteer to help in the smooth running of the day they would be more than welcome. If your T-shirt has not yet arrived do not fear as there will be spare available on the day as well as extra sponsorship forms, maps and donation slips. If you want any more information about the day’s events please contact l.newton@cancerkin.org.uk
La Boheme
On Saturday 31st July in coordination with new production company Opera Up Close, Cancerkin will be hosting their benefit performance of Puccini’s La Boheme. By now you should all have received your invitations to this exciting event. With only 7 weeks to go, ticket requests are coming in thick and fast. To be sure you don’t miss out send your form back asap to:
The Cancerkin Centre, Royal Free Hospital, Pond Street, NW2 3QG.
In the News…
Trials show revolutionary Intrabeam treatment working…
In 2008 Cancerkin donated a revolutionary piece of equipment known as the Intrabeam to the Royal Free Hospital. The machine allows surgeons to perform targeted radiotherapy whilst a patient is in theatre, thus negating the need for the patient to return to hospital for radiotherapy following their surgery. This could avoid a patient making up to a further 35 visits to hospital for post operative radiotherapy whilst reducing waiting times of patients and saving much needed NHS funds.
After a 10- year clinical trial around the world, involving 2,200 patients, results presented to the American Society of Clinic Oncology have shown the use of the Intrabeam to be safe. The findings were published in the medical journal The Lancet, with surgeons at the Royal Free stating that the process signals “the future of breast cancer treatment”. Mr Mohammed Keshtgar, consultant surgical oncologist at the Royal Free and supporter of Cancerkin said: “The most important finding is that the procedure is safe. It has fewer side effects, is as effective as conventional radiotherapy and is far more convenient for the patient who has gone through the psychological and physical trauma of having surgery for breast cancer.”
After approval from the National Institute for Clinical Excellence (NICE) it is hoped that this could be available on the NHS within 2/3 years for most breast cancer patients with early cancer who are also undergoing a lumpectomy. Projections suggest it could help up to 70% of the 50,000 patients diagnosed with breast cancer in the UK each year. Cancerkin is extremely proud of its involvement with such revolutionary work and will continue to follow the progress of the treatment with interest.
New treatment for early stage breast cancer…
Removal of the underarm lymph nodes next to a cancerous breast was long the standard treatment. However, a study involving 991 women has found that the removal of the nodes did not necessarily prolong survival or prevent recurrence of the cancer. Michael Baum, lead investigator of the radiation study at the University College London said that “The theme [of research] is now how can we improve the quality of life for women”.
All of the 991 women involved in the study had had lumpectomies, radiation therapy and a positive sentinel lymph node; while half had the other lymph nodes surrounding the breast removed the other half did not. The results show that after five years there was no difference in survival or disease recurrence between the two groups with Dr Armando Giuliano, lead investigator of the study even going so far as to call the evidence overwhelming: “The evidence is overwhelming that the operation might not be necessary,” .Dr. Giuliano did say however, the results of the study apply only to women who undergo a lumpectomy followed by radiation, not women who undergo complete breast removal, who do not typically get radiotherapy.
Some critics of the study have said that it has several shortcomings namely that the women who were tested seem to have quite favourable prognoses between them and that the study needs to encompass a larger number of women. Read the full article here
LaurenNewton 11th June 2010
l.newton@cancerkin.org.uk
Cancerkin’s News…
Hyde Park Walk…
Our Hyde Park Walk takes place this Sunday, 13th June. Registration will be between 9-10.30am with the walk finishing at approximately 2.30pm. Graeme Le Saux, ex Chelsea and England football player will be there to open the event. Entry will be available on the day so please feel free to bring anyone along with you who would like to take part. As always many hands make light work, so if you know someone who would like to volunteer to help in the smooth running of the day they would be more than welcome. If your T-shirt has not yet arrived do not fear as there will be spare available on the day as well as extra sponsorship forms, maps and donation slips. If you want any more information about the day’s events please contact l.newton@cancerkin.org.uk
La Boheme
On Saturday 31st July in coordination with new production company Opera Up Close, Cancerkin will be hosting their benefit performance of Puccini’s La Boheme. By now you should all have received your invitations to this exciting event. With only 7 weeks to go, ticket requests are coming in thick and fast. To be sure you don’t miss out send your form back asap to:
The Cancerkin Centre, Royal Free Hospital, Pond Street, NW2 3QG.
In the News…
Trials show revolutionary Intrabeam treatment working…
In 2008 Cancerkin donated a revolutionary piece of equipment known as the Intrabeam to the Royal Free Hospital. The machine allows surgeons to perform targeted radiotherapy whilst a patient is in theatre, thus negating the need for the patient to return to hospital for radiotherapy following their surgery. This could avoid a patient making up to a further 35 visits to hospital for post operative radiotherapy whilst reducing waiting times of patients and saving much needed NHS funds.
After a 10- year clinical trial around the world, involving 2,200 patients, results presented to the American Society of Clinic Oncology have shown the use of the Intrabeam to be safe. The findings were published in the medical journal The Lancet, with surgeons at the Royal Free stating that the process signals “the future of breast cancer treatment”. Mr Mohammed Keshtgar, consultant surgical oncologist at the Royal Free and supporter of Cancerkin said: “The most important finding is that the procedure is safe. It has fewer side effects, is as effective as conventional radiotherapy and is far more convenient for the patient who has gone through the psychological and physical trauma of having surgery for breast cancer.”
After approval from the National Institute for Clinical Excellence (NICE) it is hoped that this could be available on the NHS within 2/3 years for most breast cancer patients with early cancer who are also undergoing a lumpectomy. Projections suggest it could help up to 70% of the 50,000 patients diagnosed with breast cancer in the UK each year. Cancerkin is extremely proud of its involvement with such revolutionary work and will continue to follow the progress of the treatment with interest.
New treatment for early stage breast cancer…
Removal of the underarm lymph nodes next to a cancerous breast was long the standard treatment. However, a study involving 991 women has found that the removal of the nodes did not necessarily prolong survival or prevent recurrence of the cancer. Michael Baum, lead investigator of the radiation study at the University College London said that “The theme [of research] is now how can we improve the quality of life for women”.
All of the 991 women involved in the study had had lumpectomies, radiation therapy and a positive sentinel lymph node; while half had the other lymph nodes surrounding the breast removed the other half did not. The results show that after five years there was no difference in survival or disease recurrence between the two groups with Dr Armando Giuliano, lead investigator of the study even going so far as to call the evidence overwhelming: “The evidence is overwhelming that the operation might not be necessary,” .Dr. Giuliano did say however, the results of the study apply only to women who undergo a lumpectomy followed by radiation, not women who undergo complete breast removal, who do not typically get radiotherapy.
Some critics of the study have said that it has several shortcomings namely that the women who were tested seem to have quite favourable prognoses between them and that the study needs to encompass a larger number of women. Read the full article here
LaurenNewton 11th June 2010
l.newton@cancerkin.org.uk
Friday, 4 June 2010
On the pulse...for people affected by breast cancer
On the pulse
Cancerkin’s News…
Hyde Park Walk…
Our Hyde Park walk on Sunday 13th June is fast approaching but there is still time to register your entry. If you, or someone you know would like to get involved please email l.newton@cancerkin.org.uk for more information.
In the News…
Trials of breast cancer prevention vaccine set to begin…
A vaccine designed to deter the risk of breast cancer amongst young healthy women could go to clinic trial stage within the next two years. The jab, which has so far only been tested on animals, has impressed doctors so much that there is a high possibility that in the future GPs could offer the vaccine to women before they reach their mid 40s- an age when the risk of breast cancer rises.
Vincent Tuohy an immunologist at the Cleveland Clinic in Ohio, believes “that breast cancer is a completely preventable disease” and that these drugs" will provide substantial protection". The vaccine attacks a certain protein found in the majority of breast cancer cells as well as in the mammary glands of women who are breastfeeding; as a result, the jab would only be available to those who are not going to breastfeed in the future.
The trial injected 12 mice at the age of 2 months; 6 with the vaccine and 6 with a sham vaccine. All the mice were bred to be prone to breast cancer. At the 10 month period those who had received the sham vaccine had developed cancerous tumours and those who had received the protein vaccine were all clear. However, despite these figures, as with all new testing there are sizeable risks to be considered. Furthermore previous studies have shown that between 50-70% of human breast cancer cells carry the alpha-lactalbumin protein the vaccine targets – figures that suggest the jab would not destroy all of a patient's breast cancer cells.
Read the full article here
A blood test that can spot cancer before it develops…
Proteins, known as antigens are produced from cancerous cells, triggering the immune system to produce large amounts of autoantibodies. A new revolutionary blood test is said to recognise the initial signals of such a process, through monitoring the activity of a person’s immune system and the analysis of just 10ml of a patient’s blood. Research has even suggested that such signals can be detected up to 5 years before a tumour is spotted, giving doctors and patient’s vital time to fight the disease.
Professor John Robertson, a breast cancer specialist who for the past 15 years has led a team of clinicians working on the research in Nottingham and Kansas said “The earliest cancer we have seen is a cancer that has been screen detected, and yet biologically that’s late in the road of cancer development…We are starting to understand carcinogenesis in a way that we have never seen before — seeing which proteins are going wrong, and how the immune system responds. It’s as if your body is shouting ‘I’ve got cancer’ way before a tumour can be detected.” The research involved 8,000 patients and the test, known as EarlyCDT-Lung, is due to be introduced in Britain early next year.
Read the full story here
A preventative solution to the hair loss debate…?
The fear of hair loss is common amongst most women who undergo chemotherapy. Indeed only two weeks ago I reported on the risks of permanent hair loss from the chemotherapy drug, Taxotere. Chemotherapy drugs target fast-growing cells, in a bid to stop cancer reproducing at a rapid rate. Hair follicles are second only to bone marrow, in terms of their regenerative capacity, and so their growth and function is severely inhibited when in contact with a chemotherapy drug. Philip Kingsley, whose wife Joan had cancer, has suggested wearing a cool cap during treatment. Cool fluid to be pumped through the soft silicone cap which constricts the tiny capillaries that feed the hair, reducing the amount of drugs reaching the follicles. The drawback is that it can be uncomfortable and most patients can only tolerate it for about 20 minutes. Read more here
Lauren Newton 4th June 2010
l.newton@cancerkin.org.uk
Cancerkin’s News…
Hyde Park Walk…
Our Hyde Park walk on Sunday 13th June is fast approaching but there is still time to register your entry. If you, or someone you know would like to get involved please email l.newton@cancerkin.org.uk for more information.
In the News…
Trials of breast cancer prevention vaccine set to begin…
A vaccine designed to deter the risk of breast cancer amongst young healthy women could go to clinic trial stage within the next two years. The jab, which has so far only been tested on animals, has impressed doctors so much that there is a high possibility that in the future GPs could offer the vaccine to women before they reach their mid 40s- an age when the risk of breast cancer rises.
Vincent Tuohy an immunologist at the Cleveland Clinic in Ohio, believes “that breast cancer is a completely preventable disease” and that these drugs" will provide substantial protection". The vaccine attacks a certain protein found in the majority of breast cancer cells as well as in the mammary glands of women who are breastfeeding; as a result, the jab would only be available to those who are not going to breastfeed in the future.
The trial injected 12 mice at the age of 2 months; 6 with the vaccine and 6 with a sham vaccine. All the mice were bred to be prone to breast cancer. At the 10 month period those who had received the sham vaccine had developed cancerous tumours and those who had received the protein vaccine were all clear. However, despite these figures, as with all new testing there are sizeable risks to be considered. Furthermore previous studies have shown that between 50-70% of human breast cancer cells carry the alpha-lactalbumin protein the vaccine targets – figures that suggest the jab would not destroy all of a patient's breast cancer cells.
Read the full article here
A blood test that can spot cancer before it develops…
Proteins, known as antigens are produced from cancerous cells, triggering the immune system to produce large amounts of autoantibodies. A new revolutionary blood test is said to recognise the initial signals of such a process, through monitoring the activity of a person’s immune system and the analysis of just 10ml of a patient’s blood. Research has even suggested that such signals can be detected up to 5 years before a tumour is spotted, giving doctors and patient’s vital time to fight the disease.
Professor John Robertson, a breast cancer specialist who for the past 15 years has led a team of clinicians working on the research in Nottingham and Kansas said “The earliest cancer we have seen is a cancer that has been screen detected, and yet biologically that’s late in the road of cancer development…We are starting to understand carcinogenesis in a way that we have never seen before — seeing which proteins are going wrong, and how the immune system responds. It’s as if your body is shouting ‘I’ve got cancer’ way before a tumour can be detected.” The research involved 8,000 patients and the test, known as EarlyCDT-Lung, is due to be introduced in Britain early next year.
Read the full story here
A preventative solution to the hair loss debate…?
The fear of hair loss is common amongst most women who undergo chemotherapy. Indeed only two weeks ago I reported on the risks of permanent hair loss from the chemotherapy drug, Taxotere. Chemotherapy drugs target fast-growing cells, in a bid to stop cancer reproducing at a rapid rate. Hair follicles are second only to bone marrow, in terms of their regenerative capacity, and so their growth and function is severely inhibited when in contact with a chemotherapy drug. Philip Kingsley, whose wife Joan had cancer, has suggested wearing a cool cap during treatment. Cool fluid to be pumped through the soft silicone cap which constricts the tiny capillaries that feed the hair, reducing the amount of drugs reaching the follicles. The drawback is that it can be uncomfortable and most patients can only tolerate it for about 20 minutes. Read more here
Lauren Newton 4th June 2010
l.newton@cancerkin.org.uk
Friday, 28 May 2010
On the pulse....for people affected by breast cancer
On the pulse
Cancerkin’s News….
Cancerkin steps up the fundraising…
With only 2 weeks to go before our Hyde Park Walk, we are still accepting any last minute entries for the event on Sunday 13th June 2010. If you would like to enter or require any more details please contact l.newton@cancerkin.org.uk . For those of you who have entered you should have all received your t-shirts by now, so all that is left to do is to start collecting your sponsorship! GOOD LUCK!
Keep an eye on your post boxes this week for information on our Opera fundraising evening; an innovative and witty production of Puccini’s La Boheme at the Soho Theatre London on Saturday 31st July 2010. If you have any ideas for future fundraising initiatives or would like some help or information in organising one of your own please feel free to contact us at the office.
In the News…
Screening process for young women with breast cancer needs overhaul…
Breast cancer is the most common cause of death in women aged 35 to 54 and the statistics are rising, with a quarter of the 46,000 new cases of cancer diagnosed before the menopause. Awareness of the risk of cancer is low among these women as many have previously been advised that they are ‘too young to get breast cancer’. Indeed they are considered by some, ‘too young’ for free screening. NHS breast screening is only routinely available to women between the ages of 50 and 70. However, if you are below this age and have a lump and have been referred by your GP you can be screened by the NHS. Those outside this upper age bracket, who want to be safe rather than sorry must pay for it privately, or receive it as part of a corporate screening programme.
There is evidence that breast cancer detected via screening rather than symptoms, has significantly better survival rates, as it means the disease can be tackled at an early stage. Dr Nick Perry, an NHS Consultant, strongly believes that women under 50 deserve as much right to early detection via screening as older women. Dr Perry’s reports in the Daily Mail that 40% of the patients in his specific clinic are being diagnosed under 50. He continues saying: ‘It's harrowing dealing with these women - many with young children - because, with screening, some of these cases could have been picked up earlier, the women treated successfully and their lives saved. One could argue that it is all the more important for younger women to be screened, as they have a higher proportion of aggressive cancers and, therefore, most to gain from early detection.’
Research shows that women between the ages of 35-49 make up 40% of all years of life lost to breast cancer. In the U.S., where annual breast screening is available to those 40+, results show that 95% of women survive at least 5 years following diagnosis, compared to the UK’s 78.5 %. To offer national breast screening to all those at 40+ would of course have considerable financial and logistical implications. The current economic climate has left the government and the health sector with large budgetary limitations, for all the research, equipment, staff and training that would be involved in the programme redesign. Women under 50 have denser breast tissue, making small cancers harder to find using traditional mammograms, so digital mammography would be required; better at detecting cancer in dense breast tissue but also more expensive.
However, the good news is that as part of the national programme, some Primary Care Trusts around the country have recently announced that they will begin screening from the age of 47. Like such Primary Care Trusts, we at Cancerkin are also looking to serve this emergent group of young cancer suffering women. Over the next couple of weeks, we are looking to establish a Young Women’s Support Group, designed to tackle the issues that may specifically affect young cancer sufferers such as fertility, sexuality, work etc. The proceeds from our up and coming Opera fundraising evening will go towards establishing this group for the long term. If you are interested in the group please email L.newton@cancerkin.org.uk . Read all of Dr Perry’s above article here.
Breast reconstruction support…
BRA is a new Breast Reconstruction Awareness group, set up to bring women who have had mastectomies together, to exchange advice and support on issues surrounding reconstruction. reconstruction. The BRA Group: From left Jane Borland, Rhoda Reeds, Ann Gill, Pam Davis and Cat Johnson Photo: JOHN LAWRENCE The group, the brainchild of Kettering General Hospital plastic surgeon Thangasamy Sankar, founder of the group explains that while national charities such as Breast Cancer Care have post-mastectomy support groups run by medical staff, "this group is different because it's run by patients for patients. Breast reconstruction is not a life-saving operation, it's one to improve a woman's quality of life. A woman needs clear information to make a decision. And however much I describe it, I'm only a clinician. I can't tell women what it feels like." While initial treatments for breast cancer are high-profile, there is much less advice and support about
The women talk frankly about their personal experiences and feelings. Rhoda Rees, a 49-year-old receptionist and mother of two who says a mastectomy "puts a lot of people off sex. You don't feel feminine. It doesn't matter how often your partner reassures you – it's how you feel in your head. You can end up feeling totally worthless." Cat Johnson the group’s secretary and IT expert echoes Rees saying "Friends can be incredibly crass. They'd say things like 'it's only a boob, you don't need it, why not get both cut off?'" Although all the women admit the procedure to be ‘painful’, some even stating it to be worse then cancer, they all share the elation they felt when they saw the results: Rhoda Rees said "Of course it looked like a patchwork quilt with the bruising and stitches, but I felt like a woman again.", a sentiment Ann Gill shares "all you want to do is feel complete… this isn't about vanity: it's about feeling normal."
There are three different types of breast reconstruction available, all with different implications which the article talks through in depth. Read the BRA women’s stories in full here.
Genetics…
After witnessing the death of her mother and older sister to breast cancer, along with 8 other close female relatives, 47 year old Shirley McQueen , has made the radical decision to have both her breasts removed. McQueen has been advised by a genetic oncologist, Dr James Mackay that due to the large number of relatives with the disease and that all cases proved fatal, it could well be possible that Shirley’s family possess a particularly aggressive cancer gene. McQueen herself stating: "From an early age I have accepted that I am going to die, and I have prepared my son and daughter for that," says McQueen.
Jane O'Brien of the General Medical Council, recognises that "Genetics is becoming more of an issue for patients.” However, the many difficult practical and ethical issues that emerge for doctors in the genetics debate often goes unrecognised. For instance should doctors always pass on the news to children, siblings, grandchildren, that there is a risk, possibly a high risk of suffering from the same disease as other blood relatives have suffered?
Read the full article on genetics here. If you have any questions regarding genetics and your condition please speak to your consultant.
Cancerkin’s News….
Cancerkin steps up the fundraising…
With only 2 weeks to go before our Hyde Park Walk, we are still accepting any last minute entries for the event on Sunday 13th June 2010. If you would like to enter or require any more details please contact l.newton@cancerkin.org.uk . For those of you who have entered you should have all received your t-shirts by now, so all that is left to do is to start collecting your sponsorship! GOOD LUCK!
Keep an eye on your post boxes this week for information on our Opera fundraising evening; an innovative and witty production of Puccini’s La Boheme at the Soho Theatre London on Saturday 31st July 2010. If you have any ideas for future fundraising initiatives or would like some help or information in organising one of your own please feel free to contact us at the office.
In the News…
Screening process for young women with breast cancer needs overhaul…
Breast cancer is the most common cause of death in women aged 35 to 54 and the statistics are rising, with a quarter of the 46,000 new cases of cancer diagnosed before the menopause. Awareness of the risk of cancer is low among these women as many have previously been advised that they are ‘too young to get breast cancer’. Indeed they are considered by some, ‘too young’ for free screening. NHS breast screening is only routinely available to women between the ages of 50 and 70. However, if you are below this age and have a lump and have been referred by your GP you can be screened by the NHS. Those outside this upper age bracket, who want to be safe rather than sorry must pay for it privately, or receive it as part of a corporate screening programme.
There is evidence that breast cancer detected via screening rather than symptoms, has significantly better survival rates, as it means the disease can be tackled at an early stage. Dr Nick Perry, an NHS Consultant, strongly believes that women under 50 deserve as much right to early detection via screening as older women. Dr Perry’s reports in the Daily Mail that 40% of the patients in his specific clinic are being diagnosed under 50. He continues saying: ‘It's harrowing dealing with these women - many with young children - because, with screening, some of these cases could have been picked up earlier, the women treated successfully and their lives saved. One could argue that it is all the more important for younger women to be screened, as they have a higher proportion of aggressive cancers and, therefore, most to gain from early detection.’
Research shows that women between the ages of 35-49 make up 40% of all years of life lost to breast cancer. In the U.S., where annual breast screening is available to those 40+, results show that 95% of women survive at least 5 years following diagnosis, compared to the UK’s 78.5 %. To offer national breast screening to all those at 40+ would of course have considerable financial and logistical implications. The current economic climate has left the government and the health sector with large budgetary limitations, for all the research, equipment, staff and training that would be involved in the programme redesign. Women under 50 have denser breast tissue, making small cancers harder to find using traditional mammograms, so digital mammography would be required; better at detecting cancer in dense breast tissue but also more expensive.
However, the good news is that as part of the national programme, some Primary Care Trusts around the country have recently announced that they will begin screening from the age of 47. Like such Primary Care Trusts, we at Cancerkin are also looking to serve this emergent group of young cancer suffering women. Over the next couple of weeks, we are looking to establish a Young Women’s Support Group, designed to tackle the issues that may specifically affect young cancer sufferers such as fertility, sexuality, work etc. The proceeds from our up and coming Opera fundraising evening will go towards establishing this group for the long term. If you are interested in the group please email L.newton@cancerkin.org.uk . Read all of Dr Perry’s above article here.
Breast reconstruction support…
BRA is a new Breast Reconstruction Awareness group, set up to bring women who have had mastectomies together, to exchange advice and support on issues surrounding reconstruction. reconstruction. The BRA Group: From left Jane Borland, Rhoda Reeds, Ann Gill, Pam Davis and Cat Johnson Photo: JOHN LAWRENCE The group, the brainchild of Kettering General Hospital plastic surgeon Thangasamy Sankar, founder of the group explains that while national charities such as Breast Cancer Care have post-mastectomy support groups run by medical staff, "this group is different because it's run by patients for patients. Breast reconstruction is not a life-saving operation, it's one to improve a woman's quality of life. A woman needs clear information to make a decision. And however much I describe it, I'm only a clinician. I can't tell women what it feels like." While initial treatments for breast cancer are high-profile, there is much less advice and support about
The women talk frankly about their personal experiences and feelings. Rhoda Rees, a 49-year-old receptionist and mother of two who says a mastectomy "puts a lot of people off sex. You don't feel feminine. It doesn't matter how often your partner reassures you – it's how you feel in your head. You can end up feeling totally worthless." Cat Johnson the group’s secretary and IT expert echoes Rees saying "Friends can be incredibly crass. They'd say things like 'it's only a boob, you don't need it, why not get both cut off?'" Although all the women admit the procedure to be ‘painful’, some even stating it to be worse then cancer, they all share the elation they felt when they saw the results: Rhoda Rees said "Of course it looked like a patchwork quilt with the bruising and stitches, but I felt like a woman again.", a sentiment Ann Gill shares "all you want to do is feel complete… this isn't about vanity: it's about feeling normal."
There are three different types of breast reconstruction available, all with different implications which the article talks through in depth. Read the BRA women’s stories in full here.
Genetics…
After witnessing the death of her mother and older sister to breast cancer, along with 8 other close female relatives, 47 year old Shirley McQueen , has made the radical decision to have both her breasts removed. McQueen has been advised by a genetic oncologist, Dr James Mackay that due to the large number of relatives with the disease and that all cases proved fatal, it could well be possible that Shirley’s family possess a particularly aggressive cancer gene. McQueen herself stating: "From an early age I have accepted that I am going to die, and I have prepared my son and daughter for that," says McQueen.
Jane O'Brien of the General Medical Council, recognises that "Genetics is becoming more of an issue for patients.” However, the many difficult practical and ethical issues that emerge for doctors in the genetics debate often goes unrecognised. For instance should doctors always pass on the news to children, siblings, grandchildren, that there is a risk, possibly a high risk of suffering from the same disease as other blood relatives have suffered?
Read the full article on genetics here. If you have any questions regarding genetics and your condition please speak to your consultant.
Friday, 21 May 2010
On the pulse....for people affected by breast cancer
On the pulse
Cancerkin’s News….
Cancerkin Volunteers….
Cancerkin would like to say a HUGE thank you to all those who have volunteered their time this week to help us with our mail out for our forthcoming opera fundraising evening. Your efforts have been greatly appreciated!
There is still much to be done so if you are available to get involved please drop in anytime towards the beginning of the week or give the office a ring on 0207 830 2323 to check that we still need people!
For all our other Cancerkin supporters, keep an eye on your mail box for information on our exciting production of Puccini’s La Boheme at the Soho Theatre London on 31st July 2010.
Hyde Park Walk marshals….
We are still on the lookout for some volunteers to help marshal our Hyde Park Walk fundraiser on Sunday 13th June. As a marshal you will be helping with the general running of the day and assisting walkers with any problems they may have. If you would like more information or would like to volunteer please email l.newton@cancerkin.org.uk or speak to Lauren Newton at the office.
In the News…
The risk of cancer drug Taxotere…
The thought of hair loss, a common side effect from undergoing chemotherapy, makes many women anxious, with some feeling as though they have ‘lost my femininity’. Usually hair grows back a month or so after chemo has ended, however chemotherapy drug Taxotere, also known as docetaxel, has left many women with devastating long term hair loss.
Taxotere manufacturers Sanofi-Aventis, say permanent baldness is a 'very rare' complication of such treatments. However, researchers have found that as many as 1 in 16 patients using Taxotere could suffer from persistent alopecia. Following this research a leading UK cancer specialist has now called for a further detailed investigation into whether it is Taxotere alone causing the problem or whether the risk is increased when the drug is used as part of a combination of treatments.
The research has caused global outrage among patients who took Taxotere but insist they were never warned there was any possibility of permanent hair loss. Shirley Ledlie is one such and tells her harrowing story with Taxotere in the Daily Mail saying: 'I feel dreadful, not only about the way I look, but about myself,' she says. 'I am unrecognisable as the woman I once was. I avoid looking in the mirror and I hate shop windows because I see an 80-year-old, ugly old man - or someone going through chemo, which I'm not any more.' Read her full story here.
A drug for the future?
A harmless virus which can apparently reverse even seemingly untreatable forms of cancer when injected into tumours, could give thousands of patients new hope.
Lab tests have shown that Reovirus, which lives in human respiratory and gastrointestinal tracts, can help magnify the effects of radiotherapy in treating even the most advanced cancers. A total of 23 patients who had all stopped responding to traditional therapies were treated in the trial. They were however, still undergoing radiation as a form of pain relief. The patients were given 2-6 injections of Reolysin in varying measures alongside their radiotherapy treatment, with the results reported in the Clinical Cancer Research journal as either shrinking the size of their tumours or stopping it growing completely.
Dr Kevin Harrington, the study leader from the Institute of Cancer Research in London, said: ''The absence of any significant side effects in this study is extremely reassuring for future trials in patients receiving radiotherapy with the aim of curing their cancer.'' Dr Harrington continued, stating that the next steps of investigation would need to look at the effects of the treatment in patients with newly-diagnosed cancers that would normally be treated with radiotherapy alone, he said. Read the full article here
Lauren Newton 12th May 2010
l.newton@cancerkin.org.uk
Cancerkin’s News….
Cancerkin Volunteers….
Cancerkin would like to say a HUGE thank you to all those who have volunteered their time this week to help us with our mail out for our forthcoming opera fundraising evening. Your efforts have been greatly appreciated!
There is still much to be done so if you are available to get involved please drop in anytime towards the beginning of the week or give the office a ring on 0207 830 2323 to check that we still need people!
For all our other Cancerkin supporters, keep an eye on your mail box for information on our exciting production of Puccini’s La Boheme at the Soho Theatre London on 31st July 2010.
Hyde Park Walk marshals….
We are still on the lookout for some volunteers to help marshal our Hyde Park Walk fundraiser on Sunday 13th June. As a marshal you will be helping with the general running of the day and assisting walkers with any problems they may have. If you would like more information or would like to volunteer please email l.newton@cancerkin.org.uk or speak to Lauren Newton at the office.
In the News…
The risk of cancer drug Taxotere…
The thought of hair loss, a common side effect from undergoing chemotherapy, makes many women anxious, with some feeling as though they have ‘lost my femininity’. Usually hair grows back a month or so after chemo has ended, however chemotherapy drug Taxotere, also known as docetaxel, has left many women with devastating long term hair loss.
Taxotere manufacturers Sanofi-Aventis, say permanent baldness is a 'very rare' complication of such treatments. However, researchers have found that as many as 1 in 16 patients using Taxotere could suffer from persistent alopecia. Following this research a leading UK cancer specialist has now called for a further detailed investigation into whether it is Taxotere alone causing the problem or whether the risk is increased when the drug is used as part of a combination of treatments.
The research has caused global outrage among patients who took Taxotere but insist they were never warned there was any possibility of permanent hair loss. Shirley Ledlie is one such and tells her harrowing story with Taxotere in the Daily Mail saying: 'I feel dreadful, not only about the way I look, but about myself,' she says. 'I am unrecognisable as the woman I once was. I avoid looking in the mirror and I hate shop windows because I see an 80-year-old, ugly old man - or someone going through chemo, which I'm not any more.' Read her full story here.
A drug for the future?
A harmless virus which can apparently reverse even seemingly untreatable forms of cancer when injected into tumours, could give thousands of patients new hope.
Lab tests have shown that Reovirus, which lives in human respiratory and gastrointestinal tracts, can help magnify the effects of radiotherapy in treating even the most advanced cancers. A total of 23 patients who had all stopped responding to traditional therapies were treated in the trial. They were however, still undergoing radiation as a form of pain relief. The patients were given 2-6 injections of Reolysin in varying measures alongside their radiotherapy treatment, with the results reported in the Clinical Cancer Research journal as either shrinking the size of their tumours or stopping it growing completely.
Dr Kevin Harrington, the study leader from the Institute of Cancer Research in London, said: ''The absence of any significant side effects in this study is extremely reassuring for future trials in patients receiving radiotherapy with the aim of curing their cancer.'' Dr Harrington continued, stating that the next steps of investigation would need to look at the effects of the treatment in patients with newly-diagnosed cancers that would normally be treated with radiotherapy alone, he said. Read the full article here
Lauren Newton 12th May 2010
l.newton@cancerkin.org.uk
Friday, 14 May 2010
On the pulse...for women affected by breast cancer
On the pulse
Cancerkin’s News….
Lady Jakobovits
The Trustees and staff of Cancerkin are deeply saddened by the passing of Lady Jakobovits. She was a great friend, supporter and Patron of Cancerkin. The "Lady J" Lymphoedema Clinic at the Cancerkin Centre continues to see patients from 38 hospitals, hospices and clinics across Greater London. Our thoughts are with her lovely family in the USA & UK. To read more about Lady Jakobovits and her invaluable work please click here
Hyde Park Walk marshals
With our Hyde Park Walk only a month away we are appealing for volunteers to marshal the days event. As a marshal you will be stationed at a ‘marshal point’ throughout the course and provide help, assistance and encouragement to all participants. If you would like to offer your services or have any further questions please email l.newton@cancerkin.org.uk for all the details.
If you are already walking but have a husband, boyfriend, friend or children over the age of 18 who would enjoy some volunteering, please put them in contact with us. The work of a marshal is invaluable to the smooth running of the day and its overall success!
In the News…
Half of breast cancer patients 'suffer symptoms of post-traumatic stress disorder'
Agitation, anxiety, depression, nightmares, flashbacks, and mood swings are all facets of post-traumatic stress syndrome. Doctors have found that over half of breast cancer patients suffer from some or all of the above. A frightening breast cancer diagnosis, the stress of treatment, surgery and/or chemotherapy together with larger social implications i.e. giving up work, financial trouble and parenthood can often trigger the beginnings of post-traumatic stress disorder.
Studying the effects of the disease on 331 women, the researches from the Panteion University of Athens found that, overall, 45 per cent of the patients showed symptoms of post-traumatic stress disorder (PTSD). Of the women studied, many felt they had a poorer quality of life even three years after diagnosis and treatment. The researchers warn: “Knowing that breast cancer patients are susceptible to PTSD, it might be necessary for the field of medicine to create a plan in assisting cancer patients that takes into account the entire spectrum of a patient’s experience with the illness.”
If you suffer from any of the symptoms mentioned above please contact your GP. Furthermore, if you feel there is anything that Cancerkin could do to further help you please do let us know by emailing l.newton@cancerkin.org.uk
To read the full article please click here
Breast cancer genetic risk factors discovered
Scientist have come closer to identifying which women are more likely to develop breast cancer over their lifetime, after the discovery of 5 genetic variants that are believed to increase the risk of breast cancer.
The study, conducted by the Institute of Cancer Research (ICR) compared the genetic codes of more than 16,500 women with breast cancer and a family history of the disease with about 12,000 women without either and identified areas of DNA known to influence the risk of cancer. Dr Helen George, head of science information at Cancer Research UK, said: "This is by far the largest study of its kind to explore the common genetic variations that contribute to breast cancer risk. This research takes us a step closer to developing a powerful genetic test for the disease. Such a test could help doctors identify women who have an increased risk so that they can make informed decisions about how to take steps to reduce their chance of developing the disease."
However, Professor Nazneen Rahman, from the ICR, notes that scientists are yet to uncover exactly which genes are causing the heightened risk: "Our results now take the total number of gene regions linked to the risk of breast cancer to 18, but we still don't know which genes are causing this increased risk. Identifying the underlying genes and mechanisms behind breast cancer development is essential to increasing our understanding of the disease and ultimately finding new treatments."
Find the full article here
Lauren Newton 12th May 2010
l.newton@cancerkin.org.uk
Cancerkin’s News….
Lady Jakobovits
The Trustees and staff of Cancerkin are deeply saddened by the passing of Lady Jakobovits. She was a great friend, supporter and Patron of Cancerkin. The "Lady J" Lymphoedema Clinic at the Cancerkin Centre continues to see patients from 38 hospitals, hospices and clinics across Greater London. Our thoughts are with her lovely family in the USA & UK. To read more about Lady Jakobovits and her invaluable work please click here
Hyde Park Walk marshals
With our Hyde Park Walk only a month away we are appealing for volunteers to marshal the days event. As a marshal you will be stationed at a ‘marshal point’ throughout the course and provide help, assistance and encouragement to all participants. If you would like to offer your services or have any further questions please email l.newton@cancerkin.org.uk for all the details.
If you are already walking but have a husband, boyfriend, friend or children over the age of 18 who would enjoy some volunteering, please put them in contact with us. The work of a marshal is invaluable to the smooth running of the day and its overall success!
In the News…
Half of breast cancer patients 'suffer symptoms of post-traumatic stress disorder'
Agitation, anxiety, depression, nightmares, flashbacks, and mood swings are all facets of post-traumatic stress syndrome. Doctors have found that over half of breast cancer patients suffer from some or all of the above. A frightening breast cancer diagnosis, the stress of treatment, surgery and/or chemotherapy together with larger social implications i.e. giving up work, financial trouble and parenthood can often trigger the beginnings of post-traumatic stress disorder.
Studying the effects of the disease on 331 women, the researches from the Panteion University of Athens found that, overall, 45 per cent of the patients showed symptoms of post-traumatic stress disorder (PTSD). Of the women studied, many felt they had a poorer quality of life even three years after diagnosis and treatment. The researchers warn: “Knowing that breast cancer patients are susceptible to PTSD, it might be necessary for the field of medicine to create a plan in assisting cancer patients that takes into account the entire spectrum of a patient’s experience with the illness.”
If you suffer from any of the symptoms mentioned above please contact your GP. Furthermore, if you feel there is anything that Cancerkin could do to further help you please do let us know by emailing l.newton@cancerkin.org.uk
To read the full article please click here
Breast cancer genetic risk factors discovered
Scientist have come closer to identifying which women are more likely to develop breast cancer over their lifetime, after the discovery of 5 genetic variants that are believed to increase the risk of breast cancer.
The study, conducted by the Institute of Cancer Research (ICR) compared the genetic codes of more than 16,500 women with breast cancer and a family history of the disease with about 12,000 women without either and identified areas of DNA known to influence the risk of cancer. Dr Helen George, head of science information at Cancer Research UK, said: "This is by far the largest study of its kind to explore the common genetic variations that contribute to breast cancer risk. This research takes us a step closer to developing a powerful genetic test for the disease. Such a test could help doctors identify women who have an increased risk so that they can make informed decisions about how to take steps to reduce their chance of developing the disease."
However, Professor Nazneen Rahman, from the ICR, notes that scientists are yet to uncover exactly which genes are causing the heightened risk: "Our results now take the total number of gene regions linked to the risk of breast cancer to 18, but we still don't know which genes are causing this increased risk. Identifying the underlying genes and mechanisms behind breast cancer development is essential to increasing our understanding of the disease and ultimately finding new treatments."
Find the full article here
Lauren Newton 12th May 2010
l.newton@cancerkin.org.uk
Friday, 7 May 2010
On the pulse...for women affected by breast cancer
On the pulse
Cancerkin’s News….
eBay success…
Cancerkin are celebrating their first digital fundraising success story! Over the rainy bank holiday weekend our luxury 10 bed villa in Portugal seemed a welcome invitation, and indeed for one lucky winner it was. After entering into the bidding, a Cancerkin supporter won the auction at the price of £2,000. All the money from this sale will go directly to Cancerkin and will be used to continue our work throughout 2010.
If you are an avid eBay user and would like to donate all or a percentage of your sale prices to Cancerkin please get in touch with h.ahmed@cancerkin.org.uk for more information. Alternatively if you have a product or service you would like to donate please contact l.newton@cancerkin.org.uk .
Hyde Park Walk
Thank you to all those who have entered so far. We are currently waiting for the T-shirts to arrive but we envisage that the entry packs will be sent to you in the next two weeks.
If you have not yet entered but would like to get involved our website has all the relevant information, including downloadable entry and sponsorship forms. Alternatively please contact l.newton@cancerkin.org.uk
In the News…
Could Broccoli really help aid the fight against breast cancer?
A study published in the journal Clinical Cancer Research reveals that a component of the ‘superfood’ broccoli could help target cells which commonly fuel the growth of cancerous tumours.
According to researchers at the University of Michigan, a component of the vegetable, known as sulforaphane, could target and kill cancer stem cells as well as preventing new tumours from growing.
Current chemotherapies do not work against cancer stem cells. Researchers believe that eliminating the cancer stem cells is pivotal in the fight to control cancer. Prof Duxin Sun, the author of the study, said: "Sulforaphane has been studied previously for its effects on cancer, but this study shows that its benefit is in inhibiting the breast cancer stem cells.”
The research was conducted by treating mice that suffered from breast cancer with varying concentrations of sulforaphane. Using several methods to establish results, a marked decrease in cancer stem cells was found following sulforaphane treatment; the cancer cells treated with sulforaphane were also unable to generate new tumours. Sulforaphane was then tested on human breast cancer cell cultures in the lab, finding similar decreases in the cancer stem cells. Researchers are currently developing a method to extract and preserve sulforaphane.
To read the full article please click here.
LaurenNewton 5th May2010
l.newton@cancerkin.org.uk
Cancerkin’s News….
eBay success…
Cancerkin are celebrating their first digital fundraising success story! Over the rainy bank holiday weekend our luxury 10 bed villa in Portugal seemed a welcome invitation, and indeed for one lucky winner it was. After entering into the bidding, a Cancerkin supporter won the auction at the price of £2,000. All the money from this sale will go directly to Cancerkin and will be used to continue our work throughout 2010.
If you are an avid eBay user and would like to donate all or a percentage of your sale prices to Cancerkin please get in touch with h.ahmed@cancerkin.org.uk for more information. Alternatively if you have a product or service you would like to donate please contact l.newton@cancerkin.org.uk .
Hyde Park Walk
Thank you to all those who have entered so far. We are currently waiting for the T-shirts to arrive but we envisage that the entry packs will be sent to you in the next two weeks.
If you have not yet entered but would like to get involved our website has all the relevant information, including downloadable entry and sponsorship forms. Alternatively please contact l.newton@cancerkin.org.uk
In the News…
Could Broccoli really help aid the fight against breast cancer?
A study published in the journal Clinical Cancer Research reveals that a component of the ‘superfood’ broccoli could help target cells which commonly fuel the growth of cancerous tumours.
According to researchers at the University of Michigan, a component of the vegetable, known as sulforaphane, could target and kill cancer stem cells as well as preventing new tumours from growing.
Current chemotherapies do not work against cancer stem cells. Researchers believe that eliminating the cancer stem cells is pivotal in the fight to control cancer. Prof Duxin Sun, the author of the study, said: "Sulforaphane has been studied previously for its effects on cancer, but this study shows that its benefit is in inhibiting the breast cancer stem cells.”
The research was conducted by treating mice that suffered from breast cancer with varying concentrations of sulforaphane. Using several methods to establish results, a marked decrease in cancer stem cells was found following sulforaphane treatment; the cancer cells treated with sulforaphane were also unable to generate new tumours. Sulforaphane was then tested on human breast cancer cell cultures in the lab, finding similar decreases in the cancer stem cells. Researchers are currently developing a method to extract and preserve sulforaphane.
To read the full article please click here.
LaurenNewton 5th May2010
l.newton@cancerkin.org.uk
On the pulse
Cancerkin’s News….
Some banking exposure…
Lloyds TSB has publicised Cancerkin as part of marketing their banking support to charities. Cancerkin has appeared in a promotional video which is shown in branches of the bank and now posted on the news section of our website. A Cancerkin session features on the back of Lloyds’ charity customer brochure which gets wide distribution. And Lloyds has also made a generous £1,000 donation to support Cancerkin’s valuable work.
We would like to take this opportunity to thank Lloyds for their continued support and the publicity they have given us.
Portugal Villa on Ebay…
There are only 4 days remaining to bid for a holiday in a luxury 10 bed Villa in Portugal. The villa holiday has been donated to Cancerkin by one of our supporters as a fundraising drive on eBay. We are looking to raise £2,000+ to put towards Cancerkin’s work for the rest of 2010. If you would like to bid, or know anyone else who may benefit from this offer please follow this link.
We would also like to thank our generous supporter.
If you have anything that you would like to donate for us to auction on eBay please let us know.
Hyde Park Walk…
Entries to this years Cancerkin’s Hyde Park Walk have been coming in steadily and we would like to take this opportunity to thank you for your support! If you have not sent your form in yet, don’t worry, there is still time. We will be accepting applications right up until the day of the walk.
If you know of anyone else who would like to get involved please let us know and we will send them the information. To begin your sponsorship campaign, please download the form from our website.
In the News…
Could breast cancer treatment in the future be tailor-made?
Researchers from the University of California, San Francisco, tracked nearly 1,200 women who were diagnosed with ductal carcinoma in situ, or D.C.I.S. This form of cancer is often referred to as pre-cancer as the dangerous cells have not yet moved outside of the milk duct. An increase in mammogram use has meant that these cancers are detected early and so most of the women are at low risk from ever developing aggressive cancer. However because there are currently no ways to identify which lesions pose the biggest threat, most women chose to treat the threat aggressively, undergoing a combination of lumpectomy and radiation or opting for mastectomy.
The researchers collected data on 1,162 women diagnosed with D.C.I.S. across 63 San Francisco-area hospitals, following their progress for an average of 8 years. Three specific “biomarkers” which predicted higher risk of invasive cancer were identified. According to the researchers’ frameworks, if all three of these markers were present, a woman had a 20 percent individual risk of developing invasive cancer over the next 8 years. Similarly, when all the markers were negative, her risk of invasive cancer was only 4 percent. The report published online at The Journal of the National Cancer Institute found that 28 percent of the women in the study fell into the high-risk category and that currently in general cancer treatment, women with breast cancer are not typically tested for these ‘biomarkers’, called p16, COX-2 and Ki67.
Dr. Karla Kerlikowske, professor of medicine, epidemiology and biostatistics at the UCSF Helen Diller Family Comprehensive Cancer Centre. “If we can define a woman’s risk a little better then we can personalize what they want to do.”Dr. Susan Love, clinical professor of surgery at the David Geffen School of Medicine at the University of California, Los Angeles, not involved in the study said this: “It’s a great study and a good example of how we can decrease overtreatment by identifying markers which can tell us which lesions are the good ones versus which are likely to become invasive and deserve more aggressive treatment,”
The study is limited by its relatively small size and the fact that the women studied received only lumpectomy with no other therapy, which is not the standard treatment for women today. Typically, women with D.C.I.S. get lumpectomy and radiation or mastectomy. Furthermore the positive biomarkers predicted risk for invasive cancer but failed to indentify increased risk for recurrent D.C.I.S.
To read the full article please click here
Lauren Newton 29th April 2010
l.newton@cancerkin.org.uk
Cancerkin’s News….
Some banking exposure…
Lloyds TSB has publicised Cancerkin as part of marketing their banking support to charities. Cancerkin has appeared in a promotional video which is shown in branches of the bank and now posted on the news section of our website. A Cancerkin session features on the back of Lloyds’ charity customer brochure which gets wide distribution. And Lloyds has also made a generous £1,000 donation to support Cancerkin’s valuable work.
We would like to take this opportunity to thank Lloyds for their continued support and the publicity they have given us.
Portugal Villa on Ebay…
There are only 4 days remaining to bid for a holiday in a luxury 10 bed Villa in Portugal. The villa holiday has been donated to Cancerkin by one of our supporters as a fundraising drive on eBay. We are looking to raise £2,000+ to put towards Cancerkin’s work for the rest of 2010. If you would like to bid, or know anyone else who may benefit from this offer please follow this link.
We would also like to thank our generous supporter.
If you have anything that you would like to donate for us to auction on eBay please let us know.
Hyde Park Walk…
Entries to this years Cancerkin’s Hyde Park Walk have been coming in steadily and we would like to take this opportunity to thank you for your support! If you have not sent your form in yet, don’t worry, there is still time. We will be accepting applications right up until the day of the walk.
If you know of anyone else who would like to get involved please let us know and we will send them the information. To begin your sponsorship campaign, please download the form from our website.
In the News…
Could breast cancer treatment in the future be tailor-made?
Researchers from the University of California, San Francisco, tracked nearly 1,200 women who were diagnosed with ductal carcinoma in situ, or D.C.I.S. This form of cancer is often referred to as pre-cancer as the dangerous cells have not yet moved outside of the milk duct. An increase in mammogram use has meant that these cancers are detected early and so most of the women are at low risk from ever developing aggressive cancer. However because there are currently no ways to identify which lesions pose the biggest threat, most women chose to treat the threat aggressively, undergoing a combination of lumpectomy and radiation or opting for mastectomy.
The researchers collected data on 1,162 women diagnosed with D.C.I.S. across 63 San Francisco-area hospitals, following their progress for an average of 8 years. Three specific “biomarkers” which predicted higher risk of invasive cancer were identified. According to the researchers’ frameworks, if all three of these markers were present, a woman had a 20 percent individual risk of developing invasive cancer over the next 8 years. Similarly, when all the markers were negative, her risk of invasive cancer was only 4 percent. The report published online at The Journal of the National Cancer Institute found that 28 percent of the women in the study fell into the high-risk category and that currently in general cancer treatment, women with breast cancer are not typically tested for these ‘biomarkers’, called p16, COX-2 and Ki67.
Dr. Karla Kerlikowske, professor of medicine, epidemiology and biostatistics at the UCSF Helen Diller Family Comprehensive Cancer Centre. “If we can define a woman’s risk a little better then we can personalize what they want to do.”Dr. Susan Love, clinical professor of surgery at the David Geffen School of Medicine at the University of California, Los Angeles, not involved in the study said this: “It’s a great study and a good example of how we can decrease overtreatment by identifying markers which can tell us which lesions are the good ones versus which are likely to become invasive and deserve more aggressive treatment,”
The study is limited by its relatively small size and the fact that the women studied received only lumpectomy with no other therapy, which is not the standard treatment for women today. Typically, women with D.C.I.S. get lumpectomy and radiation or mastectomy. Furthermore the positive biomarkers predicted risk for invasive cancer but failed to indentify increased risk for recurrent D.C.I.S.
To read the full article please click here
Lauren Newton 29th April 2010
l.newton@cancerkin.org.uk
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